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More than 75% of Texans have COVID-19 antibodies, one of the world’s largest assessments finds

Vials of blood samples for serological testing. (Photo by UTHealth Houston)
血清学测试评估依赖于两种类型的抗体测试,以帮助确定得克萨斯州人群的百分比具有共同的19抗体。(图片由休斯顿uthealth摄)

在推出世界上最大的COVID-19抗体调查之一一年后,得克萨斯州关心,德克萨斯大学健康科学中心的公共卫生专家(休斯顿乌西卫生)和德克萨斯州卫生服务部(DSHS)估计,超过75%的德克萨斯人患有19抗抗体。

他们的另一个key findings,调查小组确定,感染后约120天,平均COVID-19抗体水平达到峰值,最早可能在感染后275至500天恢复到无法检测到的水平。此外,与完全接种疫苗的调查参与者相比,未接种疫苗并先前被Covid-19感染的人的抗体数量较低。

“得克萨斯州关心的数据向我们透露,完全疫苗接种的参与者的抗体水平明显高于仅具有自然感染的参与者。”埃里克·布威克尔(Eric Boerwinkle),博士,Dean,M。David公共卫生主席和Kozmetsky人类遗传学家族主席UTHealth公共卫生学院. “This suggests to us that vaccination may provide the highest level of protection, even for those who have had a prior COVID-19 infection and developed antibodies.”

由Uthealth公共卫生学院的公共卫生专家团队领导的血清学测试评估并由DSHS资助,依靠两种类型的抗体测试,以帮助确定哪些百分比的德克萨斯州人口具有抗体,并且可能有一定程度的程度防护侵害Covid-19。这些结果还有助于确定几乎没有症状或没有症状的个体的先前感染。

要求参与者完成有关其健康的简短调查,然后指示参与参与的诊所,以便对三种抗体测试进行血液抽血,相隔几个月。这使得调查团队能够在更长的时间内测量抗体水平,并了解免疫感染和疫苗接种可能持续多长时间。

德克萨斯州关心also had one of the largest samples in the nation of young people ages 5 to 19 years enrolled in a COVID-19 seroprevalence survey. The data revealed that more than 33% of the 3,889 Texas children who participated have antibodies to the virus, and of those, more than half (50.8%) were asymptomatic. Nearly half (44.9%) of parents reported the pandemic impacted their child’s mental health negatively.

“We are so thankful for all the Texans who volunteered to be in our survey,” saidJennifer Shuford, MD, MPH, Chief State Epidemiologist with DSHS. “We now have a better understanding of antibody levels in a diverse group of Texans with different experiences. Texas CARES participants are helping us understand the dynamics of the pandemic and what we can do to end it. And we’re not done yet.”

The survey team aims to continue to follow antibody levels over a longer period of time and will focus on enrolling more children in Texas CARES, particularly those from medically underserved communities.

With the recent U.S. Food and Drug Administration emergency use authorization granted for COVID-19 boosters, UTHealth and DSHS public health experts hope to better understand the effect of a booster vaccine on antibody levels.

德克萨斯州关心is managed by a collaborative team from UTHealth Houston, consisting of public health experts across UTHealth School of Public Health’s six campuses in Houston, Dallas, Austin, San Antonio, Brownsville, and El Paso, and in partnership with DSHS, Clinical Pathology Laboratories, and The University of Texas System.

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