Clinical Research Units

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Dedicated Clinical Research Units (CRUs) for conduct of clinical studies

CCTS CRU的任务是通过为研究人员提供专业设施,人员和建议来促进临床研究。beplay苹果手机能用吗CCT机构的调查人员可以使用任何CCTS CRU,具体取决于患者的位置以及CRUS的服务可用性。

UTHealth CRU at Memorial Hermann—Texas Medical Center

Houston, Texas

memorial

医疗主任:Miguel Escobar, MD -miguel.escobar@uth.tmc.edu

联合医学总监:Elmer Bernstam, MD -Elmer.V.Bernstam@uth.tmc.edu

运营总监:Kathy Franco, RN, BSN, CCRC -kathy.d.franco@uth.tmc.edu

Nurse Manager:Theresa Dancsak,RN,MSN-Theresa.Dancsak@uth.tmc.edu

高级临床计划经理:Cristina Dyke,MCTM-myriam.c.dyke@uth.tmc.edu

实验室的人agement:Candace Hernandez, BS -Candace.Hernandez@uth.tmc.edu

CRU办公室:713-704-4137

The UTHealth CRU at Memorial Hermann—Texas Medical Center began as the UTHealth General Clinical Research Center in 1986. The UTHealth CRU at Memorial Hermann—Texas Medical Center offers researchers an optimal on-campus resource and expanded capabilities for conducting clinical investigations and serves as an environment for training health professionals in clinical research. The CRU, located on the 3rd floor of the Robertson Pavilion in Memorial Hermann Hospital, is devoted entirely to the implementation and conduction of clinical research.

Uthealth CRU团队由5位具有各种临床背景的临床研究护士组成,2名实验室专家,1名beplay苹果手机能用吗监管专家,1名协调员和3名行政支持人员。所有工作人员,大多数人都经过协调和实验室经验进行了交叉培训,他们紧密合作,提供专业知识并为CCTS研究社区提供最佳的临床研究支持。beplay苹果手机能用吗

CRU提供了对专业核心服务的访问,例如:

  • 5间门诊和4间住院房间
  • Scheduling diagnostic tests and procedures
  • 海图室和一个医生的图表区域
  • 在协议开发的早期阶段咨询支持
  • In-patient and out-patient clinic space
  • Nursing and coordinator services
  • Regulatory monitoring
  • Lab services, including cell reconstruction and nitrogen storage
  • beplay苹果手机能用吗研究培训
  • 可以送往纪念赫尔曼医院的临床区域的CRU员工,例如重症监护病房,急诊室,手术室,临床单位,卧床诊所和诊断设施,例如成像套房
  • Administrative services, including budget development, parking validation, meal tickets, and petty cash services. Fees vary based upon protocol needs.

To use the CRU, investigators must complete the UTHealth IRIS/CCTS and MHH applications.

要从CRU中获得预算,请将您的协议发送给kathy.d.franco@uth.tmc.eduCRUscheduling@uth.tmc.edu.

UT M. D.安德森癌症中心CRU

Houston, Texas

Director:大卫·洪(David S. Hong),医学博士
Contact persons:Yagut Retondo, MHA, Department Administrator -yeretondo@mdanderson.org; Brenda Brown, RN, MSN, OCN, Admin Director, Ambulatory Infusion -bbrown1@mdanderson.org

CRU办公室:713-792-2144 -ctrc@mdanderson.org

Created in 1990, The University of Texas M. D. Anderson Cancer Center Clinical and Translational Research Center (Anderson CRU) is the dedicated UT M. D. Anderson site for complex biologically based new drug development. With its 32-room nursing area and adjacent full-function laboratory, the 12,660 sq. ft. CRU is an ideal location for performing intensive clinical trials with a focus on first-in-human Phase I and Phase II studies with rigorous time points and pharmacologic testing. The Anderson CRU provides a unique resource for physician-scientists and clinical investigators to develop new agents for the treatment of cancer and related diseases by offering coordination of multidisciplinary research, regulatory compliance, budget development, intensive and time-sensitive monitoring of patients, phlebotomy, and prompt, accurate processing, storage, tracking and shipment of specimens. Please contact the CRU office to learn more about using the space for your research.

Brownsville, Texas, CRU

Directors:约瑟夫·麦考密克,医学博士;医学博士苏珊·费舍尔·霍奇

Nurse Practitioner:Lori Campos

联系人:Norma Perez -Olazaran-norma.p.perezolazaran@uth.tmc.edu- 956-755-0695

计划经理:Rocio Uribe

Since 2004, the Brownsville CRU has been an integral part of the UTHealth General Clinical Research Center, which is now part of the CCTS. The Brownsville CCTS CRU is situated in Brownsville, TX, about a mile from the U.S.-Mexico border. The CRU is adjacent to the central Valley Baptist Brownsville Medical Center, in a suite in the Professional Building donated by the hospital. The unit is affiliated with The University of Texas School of Public Health (SPH)布朗斯维尔地区校园和its西班牙卫生研究中心beplay苹果手机能用吗,which are 10 minutes from the CRU and focus on diseases that are common in Hispanic populations. Brownsville is part of the Texas Lower Rio Grande Valley, which is about 95% Mexican American and has a high incidence of chronic degenerative diseases including diabetes, hypertension, and heart disease. The area also has severe health disparities and a high proportion of uninsured and indigent inhabitants. Through their programs, the SPH Brownsville Regional Campus, the Hispanic Health Research Center, and the Brownsville CRU work to improve the health of the local community.

布朗斯维尔·克鲁(Brownsville Cru)采用针对当地社区量身定制的独特团队方法,以在下里奥格兰德山谷(Lower Grande Valley)进行临床研究。beplay苹果手机能用吗布朗斯维尔CRU的调查人员与当地招募的研究人员合作,他们讲西班牙语和双文化,并且可以更轻松地进入难以接受的当地人。beplay苹果手机能用吗研究人员beplay苹果手机能用吗招募了受试者,并接受了人类受试者的保护以及他们正在工作的研究的复杂性,包括样本收集和临床检查以及一系列成像方式,包括心血管,肝和眼部。他们在社区内工作,包括招募房屋的房屋,以确定潜在的临床研究对象。

hispanic

布朗斯维尔CUR在营业时间和一些星期六的周一至周五开放。它由项目经理,项目协调员,超声波检查员的兼职护士从业人员和7位研究助手组成。beplay苹果手机能用吗该单元约为4500平方英尺,专门用于门诊服务,包括一个候诊室,7个检查室,用于快速样品处理和存储的实验室,工作人员和调查人员的图表,以便患者安排和调查人员的空间后续活动以及长期患者面试,工作人员和调查员会议的访谈/会议室。数据直接收集到专用的笔记本电脑上,并每天输入主数据库。设备包括几台超声波和纤维机器,垫子设备和DEXA扫描机,并设有专用的回声检查室。CRU得到了一项大约6000平方英尺的研究和CLIAbeplay苹果手机能用吗认可的诊断实验室的支持,由技术人员和研究生支持的实验室主管管理。实验室有一个大型标本档案。CRU还得到了数据管理团队的支持,该团队会协助数据输入屏幕(REDCAP和自定义),并定期清洁和分发数据库。所有数据都在大学防火墙后面。

布朗斯维尔CUR鼓励希望与下里奥格兰德山谷西班牙裔社区进行研究或参加CRU的正在进行的研究。以下在CRU中进行的研究向其他研究人员开放。

卡梅伦县西班牙裔队列(CCHC)

This is a cohort of 5000 randomly selected individuals in the community. Participants are followed up with regularly at 5-month intervals, some having been seen over 15 years. Consent includes permission to be enrolled in additional studies and genetic studies. Extensive socioeconomic, family history, and routine clinical data (including mental health data); hematological, metabolic and lipid profiles; and a range of imaging data are collected at each visit. Biological specimens are archived for metabolic, genetic, molecular, and immunological assessment. This cohort is available for studies ranging from epidemiological studies of prevalence, clinical aspects, and basic mechanisms of disease in Mexican-American populations to evaluation of intervention strategies (including vaccines) to behavior modification with opportunities for clinical studies in and extensively documented Mexican American population,

Diabetes risk nested cohort

这是由300多名CCHC参与者组成的,他们被诊断出患有2型糖尿病。这些参与者在2008年至2013年之间以3-4个月的间隔进行数据和标本归档。大多数人留在队列中进行定期随访。

心血管研究
Several studies have been conducted or are underway using cardiovascular imaging at regular intervals (EKG, carotid intimal thickness, flow mediated dilatation, echocardiograms, and ankle-brachial indices to assess peripheral artery disease). These studies in this low-income Mexican-American population are in collaboration with the UTHealth McGovern Medical School in Houston and the San Antonio Health Science Center.

肝病和肝癌的研究

几项关于肝病和肝癌的资助研究正在进行中,主要与M. D. Anderson合作。我们跟随患有连续纤维球体的参与者评估肝脏脂肪和肝纤维化,以评估进展和相关危险因素。对肝细胞癌患者及其直系亲属的研究也正在进行中。

基因组和代谢研究

与范德比尔特大学和北卡罗来纳大学等人的合作允许大多数CCHC参与者的大型芯片进行基因分型。其他研究包括在基因表达和表观遗传学变化方面研究糖尿病进展的RNASEQ研究。代谢研究包括脂质面板和大型脂肪组数据库。

COVID-19 studies

During most of 2020, cohort participants and some other outreach subjects were reached by phone on multiple occasions. Data on potential exposure to COVID-19, symptoms, and results of SARS-CoV-2 tests were documented. In September 2020, all participants were gradually brought into the CRU for full examination and follow up. This has created a large archive of participants with pre- and post-COVID specimens and data and changes in RNASeq expression are underway. As of September 2021, 300 CCHC participants have been fully studied, and the program is ongoing.

Cervical cancer studies

在下里奥格兰德山谷中,宫颈癌的发生率是美国最高的。与M. D. Anderson合作的干预研究正在进行中,以提高服务不足的筛查和治疗率。CRU正在协助这些研究,集中于未保险的妇女。

Tu Salud,Si Cuenta!
该社区外展计划使用行为新闻业通过电视,广播和报纸将消息传递给社区。它已得到广泛的评估,并得到了促销网络(社区卫生工作者)的支持。

salud

For more information on these studies, on conducting other studies in the Brownsville CRU, or on the Brownsville CRU in general, seehttp://www.hhrc.info/或者contact Christina Villarreal (Christina.villarreal@uth.tmc.edu) 956-882-6677. To use this CRU, investigators must complete the UTHealth iRIS/CCTS application.

UTHSC-Tyler临床研究中心beplay苹果手机能用吗

Tyler, Texas

Director:Debbie Fielder-clin.res@uthct.edu-903-877-7753

德克萨斯大学健康科学中心在Tyler’s CRU resides in the university’s Center for Clinical Research. As the premier academic research center in East Texas, the Center specializes in ground-breaking research that produces new treatments and therapies across a wide range of medicine. The Center is also unique in specializing in pulmonary research and conducts the most lung-related trials in the nation. The Center’s staff includes highly trained professionals that conduct research of the highest quality for the most comprehensive, cost-effective treatments possible.

The Center for Clinical Research supports all clinical trials by providing space and technology for conducting trials and through regulatory oversight of research studies. Services include:

  • 提交,激活和管理临床试验
  • Education of research staff on clinical research
  • Auditing and monitoring of active clinical trials
  • 保证新药物研究的法规合规性
  • Financial management of protocols
  • 数据安全和监视

To use the Center’s services, contact Debbie Fielder or visit the center’s website athttps://www.uthct.edu/center-for-clinical-beplay苹果手机能用吗research/.

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The staff of Tyler's CRU.

Lyndon Baines Johnson(LBJ)医院的Uthealth Cru

Houston, Texas

lbj

Director:Elmer V. Bernstam, MD -Elmer.V.Bernstam@uth.tmc.edu

联合导演:Miguel Escobar, MD -miguel.escobar@uth.tmc.edu

运营总监:Kathy Franco, RN, BSN, CCRC -kathy.d.franco@uth.tmc.edu

Nurse Manager:Theresa Dancsak,RN,MSN-Theresa.Dancsak@uth.tmc.edu

Sr. Administrative Manager:Cristina Dyke, BA -myriam.c.dyke@uth.tmc.edu

Sr. Research Nurse:Estela Acosta,BSN-Estela.A.Acosta@uth.tmc.edu

实验室的人agement:Candace Hernandez, BS -Candace.Hernandez@uth.tmc.edu

CRU办公室:713-566-4662,713-566-4258或Uthealth CRU办公室713-704-4137

The UT Health CRU at Lyndon Baines Johnson (LBJ) Hospital began in 2013 as a service to help LBJ investigators design and implement protocols and a liaison for working with the community to understand its research needs. Today, the UT LBJ CRU offers researchers resources for conducting clinical investigations and training for health professionals in clinical research. The purposes of the LBJ CRU are to facilitate collaborative research among UTHealth and M. D. Anderson investigators with LBJ clinicians and investigators, to increase research capacity and productivity among LBJ clinicians, and to increase access to cutting-edge research for a patient population that is historically underrepresented in clinical trials. The partner institutions, Harris Health System, UTHealth, and M. D. Anderson work together to identify and lower barriers to research in this indigent health care environment.

CRU办公室位于LBJ UT附件116室,完全致力于整个LBJ诊所,医院和社区外展诊所的临床研究的实施和进行。beplay苹果手机能用吗

CRU团队由1名具有广泛临床背景的临床研究护士和1位经验丰富的研究协调员beplay苹果手机能用吗组成。Uthealth Cru与护士,协调员,实验室专家和管理员一起支持UT LBJ部门。所有工作人员,大多数人都经过协调和实验室经验进行了交叉培训,他们紧密合作,提供专业知识并为UTHealth和LBJ研究社区提供最佳的临床研究支持。beplay苹果手机能用吗

CRU提供了对专业核心服务的访问,例如:

  • 在协议开发的早期阶段咨询支持
  • Nursing and coordinator services
  • Regulatory monitoring
  • Vital sign machines and ECG testing
  • 实验室服务在内,包括细胞重建和氮气存储(在UTHealth)
  • beplay苹果手机能用吗医师和员工研究培训
  • CRU staff who can be sent to clinical areas in the hospital, such as the intensive care units, emergency rooms, operating rooms, clinical units, and ambulatory clinics, and diagnostic facilities such as imaging suites
  • 行政服务,包括预算制定和小现金服务

费用根据协议需求而有所不同。

To use this CRU, investigators must complete the UTHealth iRIS/CCTS application. Please contactkathy.d.franco@uth.tmc.edu或者Estela.A.Acosta@uth.tmc.edufor a budget and to discuss study needs.

德克萨斯大学里奥格兰德谷克鲁克

德克萨斯州爱丁堡

Director:Jessica Martin, MD -Jessica.Martin@utrgv.edu-956-362-3553

联系人:Erik Hinojosa -erik.hinojosa@utrgv.edu

自成立医学院以来,得克萨斯大学里奥格兰德大学医学系内科学系就一直活跃于休斯敦CCTS计划。在得克萨斯大学里奥格兰德大学的CRU的身体场所正在进行努力。最近,Uthealth RGV在德克萨斯州韦斯拉科校园(KMC)校园内开设了一家门诊门诊诊所,自2020年以来就开始了四次CCTS Subaward Subaward Sars-Cov-2 /covid治疗临床试验。一楼的入口和足够的临床平方英尺以及考试室和行政办公室/团队空间的数量,KMC领导层为德克萨斯大学里奥格兰德分校的共同愿景和德克萨斯大学里奥分校的Uthealth的共同愿景提供了支持格兰德谷克鲁(Grande Valley Cru)。

rgv_cru

Ms. Brenda Lee Castañeda, Research Coordinator (L), and Dr. Timothy Heath (R).

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