干细胞和再生医学中心

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关于the Center

当代医学的主要重点是开发有效的疗法,以恢复人体组织和器官损失为疾病和创伤。再生医学是一个快速新兴的领域,在各种快速发展的科学学科的交汇处:干细胞生物学,组织工程,生物材料,分子生物学,免疫学和移植生物学和临床研究。beplay苹果手机能用吗隐含在修复受损的组织或器官修复的成功设计,实施和应用中,是对独特的生物学特性的依赖stem cells.

IMM的干细胞和再生医学中心的任务声明为:研究干细胞的基本特性,并将其独特的生物学特性转化为新的细胞疗法,用于移植工程和组织再生,以实现当前棘手的疾病.因此,虽然隐含任何此类程序都将跨越basic-translational-clinical research,至关重要的是,这样的努力最终得到基础干细胞研究的卓越基础。beplay苹果手机能用吗中心主任Dr. Brian R.戴维斯is currently in the process of recruiting a multidisciplinary faculty with the appropriate breadth of expertise, innovation and scientific rigor in the discipline of stem cell biology with the dual intention to promote the excellence and innovation of research within the Center and secondly to ensure the quality and appropriateness of stem cell based translational research initiatives emanating from the Center. In addition, the Center is also envisioned as an educational resource, which in the medium to long-term will be the basis for the development of an academic program in stem cell biology on campus. Moreover, by interfacing effectively with other programs and institutions within the UTHSC, the Center will also act as a focus to stimulate the development and implementation of novel cellular therapies for a range of diseases and disorders.

Some of the current areas of research in the Center are highlighted below:

Brian R. Davis博士
分子医学教授和干细胞和再生医学中心主任

Annie and Bob Graham Distinguished Chair in Stem Cell Biology
博士〜加利福尼亚理工学院 /加利福尼亚州帕萨迪纳

  • 戴维斯博士的实验室集中于遗传校正遗传突变,目的是推导适合移植的细胞。当前的研究重点是开发肺部疾病(囊性纤维化和表面活性剂蛋白B缺乏症)和血液疾病(镰状细胞贫血和Wiskott-Aldrich综合征)的疗法。

Charles S. Cox, Jr., M.D.
教授, Department of Pediatric Surgery & Center for Stem Cell and Regenerative Medicine

M.D.〜德克萨斯大学医学分公司 /德克萨斯州加尔维斯顿

  • Cox博士是儿童基金会。小儿手术杰出教授,并指导Uthealth医学院再生医学的儿科外科翻译实验室和儿科计划。他在德克萨斯医学中心的Uthealth医学院/儿童纪念赫尔曼医院指导儿科创伤计划。

Radbod Darabi, M.D., Ph.D.
副教授of Stem Cell Biology, Center for Stem Cell and Regenerative Medicine

M.D. ~ Zahedan University of Medical Sciences / Zahedan, Iran
博士~ Tehran (Iran) University of Medical Sciences / Tehran, Iran

  • Dr. Darabi's laboratory is focused on study of therapeutic potential of pluripotent stem cells for skeletal and cardiac muscle regeneration. Directed differentiation of stem cells into various tissue progenitors is another area of his research interests.

Sarah Xuelian Huang,MB.B.S.,博士
Assistant Professor of Stem Cell Biology, Center for Stem Cell and Regenerative Medicine

MB.B.S.
博士~ Columbia University / New York, New York

  • 黄博士的实验室有兴趣应用人类多能干细胞在肺正常和病理发育的背景下研究细胞命运规范的基本机制。长期目标是将获得的知识转化为预防和治疗当前无法治愈的肺部疾病。

Dong H. Kim, M.D.
教授, The Vivian L. Smith Department of Neurosurgery & Center for Stem Cell and Regenerative Medicine

M.D.〜加利福尼亚大学,旧金山 /加利福尼亚州旧金山

  • As Director of the Mischer Neuroscience Institute (MNI) since October 2007, Dr. Kim leads the clinical neuroscience efforts for the Memorial Hermann Healthcare System and UTHealth. Dr. Kim is noted for his research into the origin, development and treatment of brain aneurysms. He leads basic science efforts, such as identifying the genes that lead to an inherited risk for aneurysms and genetic changes in brain tumors, and translational projects that directly affect clinical practice.

纳米·麦卡蒂(Nami McCarty)博士
干细胞和再生医学中心教授

博士- Purdue University / West Lafayette, Indiana

  • The main focus of Dr. McCarty’s laboratory is to understand cellular and molecular mechanisms of stem cell fate determination and development in hematological malignancies. Developing targeted therapies inhibiting development of the stem-like cells in blood cancers is a major goal in her lab.

Pamela L. Wenzel, Ph.D.
综合生物学和药理学系副教授,干细胞和再生医学中心

博士,美国俄亥俄州立大学/ Columbus, Ohio

  • Wenzel博士的研究重点beplay苹果手机能用吗是研究各种外部因素,包括生物力学,可溶性分子和药理学化合物,使早期血细胞能够为成人血液系统做出贡献。她现在正在应用这些见解,以提高各种干细胞类型促进脑损伤中修复的能力。

Jiaqian Wu博士
Vivian L. Smith神经外科和干细胞中心副教授,再生医学中心

博士学位 - 贝勒医学院 /德克萨斯州休斯顿

  • Dr. Wu’s laboratory combines stem cell biology and system-based approaches involving functional genomics and next-generation sequencing technologies to unravel gene transcription and regulatory mechanisms governing neural differentiation. Her goal is to identify key regulators during this process as therapeutic targets and develop safe treatment for spinal cord injury and neurological diseases.

Momoko Yoshimoto, M.D., Ph.D.
干细胞和再生医学中心分子医学副教授

MD- MIE大学医学院 /日本TSU
PhD- Kyoto University Graduate School of Medicine / Kyoto, Japan

  • Dr. Yoshimoto’s lab is focusing on the development of the innate-like B-1 lymphoid cells and hematopoietic stem cells (HSC) in the mouse embryo. Prior to the emergence of the first HSC, various types of hematopoietic progenitors are produced from hemogenic endothelial cells in an HSC-independent manner. Dr. Yoshimoto’s lab is trying to elucidate the molecular mechanisms that mature the hematopoietic potential of hemogenic endothelial cells, utilizing lineage tracing mouse model, transplantation assays, and RNA-sequencing studies.