Laboratory of Eunhee Kim, Ph.D.

OVERVIEW

Research in the Eunhee Kim laboratory is focused on evaluating molecular and genetic mechanisms, biomarkers, and the inflammatory response involved in stroke and brain arteriovenous malformation (bAVM). The ultimate research goal is to translate the findings into novel therapeutic strategies for the patients.

Stroke is one of the major causes of disability and death worldwide, however there are limited treatment options available for the stroke patients. Several risk factors such as hypertension, dyslipidemia, and diabetes have been involved in the higher stroke incidence and poorer outcomes, but the underlying mechanism(s) of the negative impact is not clear. By incorporating the risk factors in animal models of stroke, Dr. Kim is particularly interested in investigating how post-stroke stress response is regulated in the comorbid conditions, and how it affects stroke-induced immune response and stroke outcomes including acute injury and long-term recovery.

另一项研究的重点是理解脑动脉畸形beplay苹果手机能用吗（BAVM）的病理生理学。BAVM是年轻患者出血性中风的关键危险因素，但是，BAVM的病因和病理学在很大程度上尚不清楚。Kim博士目前正在研究BAVM病理生理学中与内皮功能障碍，血管生成和炎症有关的几种分子因子的作用。通过调节因素体内和体外, the ongoing bAVM research includes generating a clinically-relevant bAVM animal models and defining the underlying mechanisms in bAVM formation and pathology, and investigating the subsequent impact of bAVM in cerebral hemorrhage.

Dr.Eunhee Kim是德克萨斯大学健康科学中心的Vivian L. Smith神经外科助理教授。Kim博士在韩国首尔的Kyung Hee大学获得博士学位。在博士学位期间，她专注于内分泌疾病（如肢端肿瘤和糖尿病）中生长激素轴的调节。在神经内分泌学的背景下，她加入了伯克医学研究所的Cho Lab博士，参加了博士后培训，并于2013年在Weill Cornell Medicine的Feil Famibeplay苹果手机能用吗ly Brain和Mind Research Institute担任教练。Kim博士获得了脑血管病理生理学的丰富经验，并通过特定的培训体内和体外缺血性中风的研究。她定义了炎症介质的作用，CD36在高脂症和糖尿病状况中的急性中风结果以及与合并症有关中风的基本机制中的作用。她还参与研究突触可塑性对中风后长期功能恢复的重要性以及使用人BDNF多态性动物模型的遗传学作用。这些作品已在包括神经学纪事,神经科学杂志，和脑血流和代谢杂志。

当前的项目

压力反应对急性中风损伤和糖尿病状况长期恢复的影响
Role of brain endothelial KRAS mutation in bAVM formation and pathology
Role of neuroinflammatory response in endothelial dysfunction and bAVM pathology

团队成员

Eunsu Park, Ph.D, Postdoctoral Research Fellow

接触

电子邮件：Eunhee.kim@uth.tmc.edu

办公室电话：713-500-6837

Laboratory of Eunhee Kim, Ph.D.

OVERVIEW

当前的项目

团队成员

接触

最新出版物