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临床和转化科学中心解决了德克萨斯州的Covid-19

参加了休斯敦举行的2021 CCT年度会议的专业人员的小组照片。(Rogelio Castro/Uthealth摄影)
构成临床和转化科学中心的八个机构的成员在其2021年的休斯顿年度会议上拍摄。(Rogelio Castro/Uthealth摄影)

临床和转化科学中心及其七个学术卫生机构合作伙伴利用了15年以上建立的关系,以迅速应对Covid-19-19的大流行。随着新发现并开发了疗法,他们的合作努力有助于促进从研究人员到临床医生的信息流,最终有助于挽救生命。beplay苹果手机能用吗

转化科学是研究重点进行协作的研究框架。beplay苹果手机能用吗目的是翻译实验室研究和科学发现,并将它们迅速带入临床实践以beplay苹果手机能用吗解决健康问题。信息流还包括将知识应用于人口健康的公共卫生工作者。

The Center for Clinical and Translational Sciences was first established in 2006 by the University of Texas Health Science Center at Houston (UTHealth), The University of Texas MD Anderson Cancer Center, and Memorial Hermann Health System with one of the National Institutes of Health’s inaugural临床和转化科学奖。The center is now in its third funding cycle. In 2021 alone, the center brought more than $26.8 million in NIH grants to Texas to combat the pandemic, particularly among vulnerable populations.

“因为我们建立合作渠道, the Center for Clinical and Translational Sciences was immediately prepared to respond to clinical trial needs for COVID-19 almost overnight,” said Michael Blackburn, PhD, UTHealth executive vice president and chief academic officer. “We are proud of the group and what it has accomplished. Throughout the pandemic there were conversations with the governor and other Texas officials, and people from across the country who reached out to us. The team structure we have in place enabled us to react quickly and help communities, and the impact it has had on the nation has been great.”

The Center for Clinical and Translational Sciences, under the leadership of UTHealth, is one of the largest in the country, reaching 14.5 million people in Texas and western Louisiana. It is also one of the most diverse, serving a population that is 37% Hispanic and including a large rural and economically challenged population.

在大流行期间,该中心通过增加路易斯安那州立大学卫生什里夫波特和德克萨斯大学里奥格兰德大学的卫生大学卫生大学卫生大学的占地面积扩大了其在得克萨斯州东北部和德克萨斯州南部的占地面积。

其他成员包括德克萨斯理工大学健康科学中心El Paso,Uthealth公共卫生学院布朗斯维尔校园,泰勒大学德克萨斯大学健康科学中心以及医学博士Anderson,Uthealth和Rice University的德克萨斯医学中心机构。

“The Lower Rio Grande Valley is 93% Hispanic overall,” said David McPherson, MD, executive director and one of the principal investigators. “It is a highly vulnerable area along the U.S.-Mexico border. Chronic disease disparities are prevalent, and those disparities contributed to how hard COVID-19 hit the area, resulting in a case fatality rate that is almost double that of the state and the country. A lot of focus during the pandemic has been addressing that and doing research around it.”

临床和转化科学中心项目包括几项针对全州脆弱和服务不足人口的测试差异的举措和非裔美国人的人口。

该中心合作使用康复等离子体作为COVID-19治疗,包括与纽约另一家NIH资助的中心合作。德克萨斯州的临床和转化科学中心招募了全国所有受试者的25%,自参加试验以来就已经招收了超过50%的受试者。

另一个项目是研究药物以防止在家中从Covbeplay苹果手机能用吗id-19恢复的人们的血凝块,以及一项住院试验,以检查减少疾病过度活跃的免疫作用的方法。其他试验旨在检查重新利用的药物是否可以减少中度COVID-19症状的持续时间和严重程度,如果是的,则可以跟踪严重Covid-19患者的住院和死亡率的影响。

The center is one of three sites chosen nationally to improve participation in the NIH’s National COVID Cohort Collaborative as well as in the All of Us program, which aims to gather health data from 1 million Americans.

As vaccine distribution rates increase across the country, the center’s work continues. It has applied to create a consortium of 14 institutions spanning six states to study “long-haul” COVID-19 symptoms.

The center is also involved in work to improve COVID-19 vaccination among Houston’s Black community, Houston residents experiencing homelessness, the Rio Grande Valley Hispanic community, East Texas rural Hispanic and non-Hispanic communities, and North Louisiana rural Black and non-Hispanic communities. The work includes collaborating with other agencies to offer education, motivation, support, and new resources to medically underserved and vulnerable communities and to individuals with other health conditions.

临床和转化科学中心的主要研究人员是Uthealth McGovern医学院内科医学院主席David McPherson;Uthealth生物医学信息学学校院长Jiajie Zhang;MD Anderson研究癌症治疗系教授Daniel Karp,医学博士;MD Anderson翻译研究副总裁Robert Bast Jr.beplay苹果手机能用吗迈克尔·布莱克本(Michael Blackburn)博士,医学博士Anderson Uthealth生物医学科学研究生院长,是国家研究生培训的国家研究服务服务奖首席研究员,该奖项是根据父母奖的独立核心赠款资助。beplay苹果手机能用吗Uthealth临床研究和医疗保健质量副副总裁Charles“ Trey” Miller III博士是学院机构职业发展计划的首席研究员。beplay苹果手机能用吗Uthealth的Maureen Goode博士是临床和转化科学中心的行政总监。

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