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德克萨斯大学健康科学中心的故事(休斯顿乌西顿)

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休斯顿休斯顿研究人员发现有关群集头beplay苹果手机能用吗痛的新发现

一项国际调查发现,有27.5%的参与者在儿童中经历了头痛,但只有15.2%的儿科发作参与者在18岁之前被诊断出。
一项国际调查发现,有27.5%的参与者在儿童中经历了头痛,但只有15.2%的儿科发作参与者在18岁之前被诊断出。
马克·伯里什(Mark Burish),医学博士,博士assistant professor in the Vivian L. Smith Department of Neurosurgery with McGovern Medical School at UTHealth Houston
马克·伯里什(Mark Burish),医学博士,博士assistant professor in the Vivian L. Smith Department of Neurosurgery with McGovern Medical School at UTHealth Houston

根据德克萨斯大学健康科学中心的研究,通常在儿童时期开始衰弱的集群头痛,但通常要诊断出患者直到成年人。beplay苹果手机能用吗休斯顿乌西卫生)。

一组研究人员beplay苹果手机能用吗马克·伯里什(Mark Burish),医学博士,博士休斯顿Uthealth Huston的McGovern医学院Vivian L. Smith神经外科部门的助理教授,进行了群集头痛问卷,这是一项基于Internet的,基于Internet的调查,对1,604名参与者,患有集群头痛。调查的结果最近发表在Headache: The Journal of Head and Face Pain

丛集性头痛是一种罕见的障碍,头痛的职业rring in about one in every 1,000 individuals. They are extremely painful and occur in cyclical patterns known as cluster periods, with most attacks taking place at the same time each day. Cluster headache is diagnosed as “episodic” when the attacks occur in periods lasting between seven days and one year and are separated by pain-free periods lasting three months or longer. Meanwhile, in “chronic” cluster headache, attacks occur for more than one year without remission or with remissions lasting less than three months.

头痛与偏头痛相似,但存在一些关键差异。与偏头痛不同,偏头痛可能会持续一整天或可能几天,如果没有治疗,群集头痛通常持续15到180分钟。虽然每天有多个偏头痛并不常见,但在24小时内,某人最多可能会头痛。此外,偏头痛的位置可能会有所不同。相比之下,簇头痛仅涉及头部的一侧,通常在寺庙或眼睛周围。最后,患有偏头痛的人倾向于在一个安静,黑暗的房间里休息,而头痛的人往往会变得不安,并且经常在房间周围步伐。

关于聚类头痛的几种特征,即小儿发作的簇头痛和簇头痛治疗的比较有效性,有极其有限的信息。

“我希望这项研究将改变传统的思想,即聚类头痛只会影响成年男性,”伯里什(Burish)也是德克萨斯大学医学博士Anderson癌症中心Uthealth生物医学科学研究生院。“我们的研究表明,它通常始于童年,而且许多儿童在没有正确诊断的情况下经历了多年的时间,大概是由于没有正确的治疗而遭受的痛苦。”

Significantly, pediatric onset was found in 27.5% of survey participants, but only 15.2% of participants with pediatric onset were diagnosed before the age of 18.

While the reasons behind this trend remain unknown, Burish has come up with several theories based on conversations with pediatric neurologists, patients, and their parents. Family members and doctors are not recognizing it because it is rare, and patients are not being referred to the appropriate specialists. Also, features of cluster headache in children could be different than they are in adults, considering that there are small differences between children and adults in other headaches like migraine.

Burish说,这项研究还表明,患有簇头痛的女性报告说,疼痛强度更高,恶心和抑郁得分更高。

其他关键调查结果包括:

  • While previous studies have shown that women are more likely to have migraines between ages 10 and 50, the inverse is true for cluster headaches: Men were more likely to have episodic cluster headache between ages 10 and 50. The sex ratio was approximately equal for other ages.
  • 绝大多数受访者至少有一种症状具有自主神经系统的反应,例如红眼或鼻塞(99.0%)(99.0%),并且躁动不安(96.6%),但许多人也具有原型的偏头痛特征,包括对光和光和光的敏感性。声音(50.1%),疼痛因体育活动加剧(31.4%)或恶心和呕吐(2​​7.5%)。
  • Interestingly, the first-line medications for acute treatment (oxygen) and preventive treatment (calcium channel blockers) were perceived as significantly less effective in chronic cluster headache compared with episodic cluster headache.

除了这一流行病学数据外,Burish说,这项研究发掘了一些值得未来研究的信息。beplay苹果手机能用吗

Burish说:“与没有家族病史的患者相比,患有聚类头痛的患者的患者的头痛似乎是从年轻的年龄开始的,” Burish说。“在遗传学中,这称为'预期',这表明可能存在一个基因或基因。识别这些基因可能是群集头痛的巨大突破。”

其他研究人员beplay苹果手机能用吗包括Uthealth公共卫生学院生物统计学和数据科学系副教授Hongyu Miao,博士学位;联合首先的作者Larry I. Schor博士和马萨诸塞州的Stuart M. Pearson与西乔治亚大学一起;以及佛蒙特大学的医学博士Robert E. Shapiro博士。Wei Zhang博士是Uthealth公共卫生学院生物统计学和数据科学系的助理教授,也是研究团队的一部分。beplay苹果手机能用吗

该研究获得了Automanic Technologies,Inc。和ClusterBusters的资金支持。

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