IBC指南
PURPOSE
休斯敦德克萨斯大学健康科学中心(UTHealth) Institutional Biosafety Committee (IBC) reports to the UTHealth Executive Vice President for Academic &Chief Academic Officer关于与使用传染性剂和/或重组和合成脱氧核糖核酸（RDNA）技术有关的问题，在UTHealth的研究，临床和教育活动中。beplay苹果手机能用吗该委员会负责确保完全遵守CDC/NIH Biosafety in Microbiological and Biomedical Laboratories (BMBL), NIH Guidelines for Research Involving Recombinant and Synthetic Nucleic Acid Molecules(referred to herein as the NIH Guidelines) and the UTHealth Institutional Biosafety Manual. The most recent version of the BMBL (2009) is available on the CDC’s website (https://www.cdc.gov/biosafety/publications/bmbl5/）并应适用于UTHealth进行的所有传染剂研究。beplay苹果手机能用吗最新版本的NIH Guidelines(April 2016) is available at the NIH Office Science Policy (NIH OSP), Biosafety, Biosecurity, and Emerging Biotechnology Policy Division (formerly known as the OBA) website (https://osp.od.nih.gov/biotechnology/nih-guidelines/）并应适用于在UTHealth进行的所有RDNA研究，无论Rbeplay苹果手机能用吗DNA研究项目资金来源如何。
Specific tasks of the committee include:
- 向学术执行副总裁推荐Chief Academic Officerpolicies and procedures that ensure the health and safety of all individuals within UTHealth, and to ensure compliance with all applicable federal, state and local statutes, regulations, procedures and principles relating to the purchase, storage, use, and disposal of biological hazards and/or rDNA used in UTHealth research, clinical and educational programs.
- To assess the safety of rDNA research experiments and recommend policies and procedures to ensure the health and safety of all faculty, staff, students, patients, and visitors within UTHealth.
- To review the protocols provided by principal investigators, clinical directors or laboratory instructors relating to the use of biological hazards and to review the activities of EH&S in verifying the appropriate biosafety containment level of those laboratories, clinics and/or practices. Activities requiring work at Biosafety Level 2 and greater may not initiate without written consent of the IBC.
- 向学术执行副总裁推荐Chief Academic Officer对研究，临床和教学活动的一般和特定培训计划的需求，包括传染性药物和/或rDNA在内，并审查此类UTHEADY培训beplay苹果手机能用吗计划的适当性和有效性。
- 至少每年提交报告，向学术执行副总裁＆Chief Academic Officer总结活动并审查一年中确定的重大生物安全问题的状态。
- 批准首席研究人员（PI），其实验室和/或在分级生物安全水平上工作的实践NIH Guidelines。
- 监督书面生物安全计划的制定和维护，这些计划指定实践，以最大程度地减少对传染性生物学剂和/或rDNA的职业接触（包括对所有受影响人群的生物和含有rDNA的生物和含有rDNA的病毒的接触）控制和工作实践；向机构社区提供该计划；根据需要，推荐该计划的更新；并监督与传染性生物学，rDNA和生物安全有关的教育计划的制定和实施。
- 确定承担暴露于传染性药物，rDNA和涉及职业群体的任务。
- 监督那些潜在暴露于感染剂和/或rDNA的人的随访和监测。
- Respond to all public comments/recommendations on IBC actions. IBC will also notify NIH Office of Science Policy in writing of posed questions and response given.
UTHealth Environmental Health and Safety (EH&S) is designated as the monitoring and effector arm of the IBC to ensure the details specified in protocols are feasible and appropriate.
All activities of the committee are coordinated, as necessary, with other institutional components including the Office of Sponsored Projects (OSP), UT Employee Health Services, Center for Laboratory Animal Medicine and Care (CLAMC) and other UTHealth oversight committees, such as the IRB [Committee for the Protection of Human Subjects (CPHS)] and the IACUC [Animal Welfare Committee (AWC)].
COMMITTEE MEMBERSHIP
作品：
The IBC consists of a minimum of five voting members so selected that they collectively have experience and expertise in various infectious agents, rDNA technology, infection control and the capability to assess the safety of rDNA research and to identify any potential risk to public health or the environment. At least two members shall be unaffiliated with UTHealth (except as members of the IBC) and shall represent the interest of the surrounding community with respect to health, safety, and the protection of the environment. At least one member shall be a scientist with expertise in animal containment principles for studies requiring approval by the IBC. At this time there is no recombinant plant research being conducted at UTHealth; however, if this research is proposed to the committee in the future then at least one member will be sought out with expertise in plant, plant pathogen, or plant pest containment principles for review of those studies.
The current UTHealth committee is comprised of the following voting members serving on three-year, staggered terms of appointment:
- 三个或三个以上教员与我的经验nfectious agent research, infection prevention, rDNA technology and/or biological safety and containment *
- 两个或两个以上的社区成员 *
- 学生成员
- A laboratory technician *
- 实验室动物医学和护理代表中心
Ex Officio成员 - 以下内容被指定为无投票的成员：
- 法律事务代表
- 安全，健康，环境和风险管理副总裁
- Safety Manager, Biological Safety Program
- 环境保护计划安全经理
- Executive Vice President and Chief Academic Officer
- Employee Health Clinical Services representative
*要求成员NIH Guidelines for Research Involving Recombinant DNA Molecules
The current list of IBC members can be found online at://www.tjghsg.com/safety/biological-safety/institutional-biosafety-committee.htm