事先批准
In general, the Principal Director (PD)/Principal Investigator (PI) may make changes in the methodology, approach, or other aspects of the project objectives. However, a change in scope and/or expenditures almost always requires sponsor approval unless special permission is given within the award agreement. A change in scope is a change in the direction, aims, objectives, purposes, or type of research training, identified in the approved project. Please keep in mind, requests must be sent to agency from AOR不迟于30天before proposed change. Please allow time for SPA to process.
Summary of Actions Requiring NIH Prior Approval
Actions likely to be considered a change in scope or objectives include, but are not limited to, the following:
- Change in the specific aims of the project and approved at the time of award.
- Substitution of one animal model for another.
- Any change from the approved use of animals or human subjects.
- Shifting the emphasis of the research from one disease area to another.
- 应用新技术，或从被批准使用其他类型的测定法的人那里进行更改。
- Transferring the performance of substantive programmatic work to a third party by contract or any other means.
- Change in key personnel whose expertise is critical to the approved project.
- 重大预算是否需要根据预算更改的规则批准。当目前预算期间的直接成本类别中的转移累计转移数量超过授予总额的25％或$ 250,000时，就会发生重大预算。
- 患者护理费用以前未批准和/或何时受赠人希望将预算资金退出患者护理类别。
- Additional no-cost extension greater than 12 months
所有事先批准的请求必须以书面形式，正式化并伴随支持文件，以确保更改合理且适当。书面请求必须提交给预先授予的，以进行审查，处理和提交。
To obtain sponsor approval, the PI must draft a justification letter on University letterhead. The letter must be signed by the department head and forwarded to the assigned Pre-award Sponsored Projects Administrator. Also include a signature block for a University authorized signing official.
事先批准请求应包括：
- 大学信件的理由信
- PI信息
- 完整的授予号
- ERA CONSONS中列出的赠款管理官
- Applicable approvals