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Study finds transport by mobile stroke units get patients quicker treatment than traditional ambulance

Photo of Amanda L. Jagolino-Cole, MD,  and Alexandra Czap, MD in front of the UTHealth mobile stroke unit. (Photo credit: J. Daniel Escareño/UTHealth)
Amanda L. Jagolino-Cole, MD, and Alexandra Czap, MD, published research that highlights the advantages of hospital transport in a mobile stroke unit versus a traditional ambulance. (Photo credit: J. Daniel Escareño/UTHealth)

中风患者的每一秒都计算,因为研究表明他们每分钟可能会损失多达2700万个脑细胞。beplay苹果手机能用吗德克萨斯大学休斯顿分校健康科学Beplay体育中心中心(UTHEALTH)的研究人员最近发表了新发现Strokethat show patients transported to the hospital by mobile stroke unit instead of standard ambulance received a clot-busting procedure an average of 10 minutes faster, which could potentially save up to 270 million neurons per patient.

In 2014, McGovern Medical School at UTHealth was the first in the nation to launch a mobile stroke unit, a specially equipped ambulance for diagnosing and treating stroke rapidly before hospital arrival.

“我们得到恢复血液流量的中风受害者治疗的越快,我们可以节省的脑组织就越多,” McGovern医学院神经病学系的血管神经病学研究员Alexandra Czap说。“这项研究表明,像我们这样的移动中风单元可以有效地简化治疗时间,潜在地节省神经功能,并最终改善中风患者的生活质量。”

该研究研究了来自休斯顿16例患者和2014年其他两个地方的数据,他们在患有急性缺血性中风后接受了动脉内血栓切除术,这是最常见的类型,是由脑动脉​​阻塞引起的。唯一已知治疗缺血性中风的药物疗法,组织纤溶酶原激活剂(TPA),并不总是能够清除大凝块。为了执行该手术,也称为血管内血栓切除术,一名血管神经科医生通常通过腹股沟动脉将导管螺纹到阻塞,在那里,插入导管中的小型装置用于去除凝块。

“This is a hallmark paper because it shows that pre-hospital evaluation and management on a mobile stroke unit can significantly reduce time to endovascular treatment for patients with large artery clots,” said Amanda L. Jagolino-Cole, MD, a teleneurologist and assistant professor in the Department of Neurology at McGovern Medical School, who was the senior author of the paper.

While on board the unit, an interdisciplinary team can begin the process to assess whether the patient needs a thrombectomy, including diagnostic imaging, neurological exam, and the administration of tPA. That gives the treatment team a head start and upon arrival to the hospital, the patient can be taken quickly to the endovascular suite for the procedure.

“Our mobile stroke unit allows us to bring the hospital to the patient,” Czap said. “We can complete the necessary diagnostic testing and notify the hospital that we are coming, so that the appropriate teams can be ready. Streamlining this process allowed for one of our recent mobile stroke unit patients to complete treatment in under two hours from onset of symptoms. Going forward, identification of possible thrombectomy candidates on the unit can increase the accuracy of triage and increase the number of patients having the procedure, which we hope will lead to better patient outcomes.”

本文还展示了一个总体改善结束ovascular thrombectomy metrics for all patients regardless of how they arrived to the hospital. This is significant because the procedure just started to be recognized as standard management for select stroke patients within the last five years, Jagolino-Cole said.

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This research is part of the ongoingBEST-MSU study,与紧急医疗服务的标准管理相比,一项前瞻性比较有效性试验,调查了使用移动中风单元提供的中风治疗的好处。主要结果是90天后患者的功能状况以及长期的医疗保健利用。最佳MSU研究将在2020年完成入学。

Co-authors included Stephanie A. Parker, RN, BSN, program director for the Mobile Stroke Unit at UTHealth; and James Grotta, MD, director of stroke research at Memorial Hermann-Texas Medical Center and the vascular neurologist who led the effort to launch UTHealth’s mobile stroke unit. Jagolino-Cole and Grotta are members of theUTHealth Institute for Stroke and Cerebrovascular Disease.

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