Biography

Dr. Amir Khan was named the 2018 Dr. James “Red” Duke, Jr., Physician Leadership Award recipient. Dr. Khan is the current Medical Director of Children’s Memorial Hermann Hospital’s NICU, co-chair of the Neonatology CPC and Professor of Pediatrics, Division of Neonatology at McGovern Medical School at UTHealth.

TheDr. James “Red” Duke, Jr., Physician Leadership Awardhonors the life and legacy of iconic surgeon and educator, Dr. Duke, and his contributions, dedication and service to health care that have made a lasting impact on medicine, education and the medical community. The award is given to a physician who is part of the Memorial Hermann Clinical Integration and/or currently serves as a board member on any of the Memorial Hermann boards and committees, demonstrates strong leadership skills, strong business acumen and work with other Memorial Hermann entities to find innovative ways to improve the health of the people we serve.

Many of the successes Memorial Hermann has experienced in neonatology have been possible due to Dr. Khan’s incredible leadership. Under Dr. Khan’s leadership, a higher quality of care for neonates has resulted in shorter hospital stays, decreased infections and complications, as well as better serving the needs of new patients.

教育

Graduate School
Aga Khan University, Karachi, Pakistan, 1989
Pediatric Residency
University of Texas-Houston Medical School, Houston, Texas, 1991-1994
新生儿 - 境内医学奖学金
University of Texas-Houston Medical School, Houston, Texas, 1994-1998

Areas of Interest

Research Interests

  • Lung inflammation in meconium aspiration syndrome
  • Gene-environment interactions and development of childhood asthma
  • GERD and chronic lung disease
  • 新生儿肺部疾病中的通气策略
  • 在新生儿和小儿呼吸衰竭中使用ECMO

Publications

Publication Information

完整的已发表工作清单

  • Klaus g。托马斯（Eric J。）；汗，阿米尔; Ottosen, Madelene J.; Yager, Lauren Implementing a Robust Process Improvement Program in the Neonatal Intensive Care Unit to Reduce Harm, Journal for Healthcare Quality: January/February 2022 – Volume 44 – Issue 1 – p 23-30 doi: 10.1097/JHQ.0000000000000310
  • 温柔的SJ，Carper B，Laughon MM等。无创呼吸支持的持续时间和支气管肺发育不良或死亡的风险[在线印刷前在线发布，2022年1月15日]。J Perinatol。2022; 10.1038/s41372-021-01269-2。doi：10.1038/s41372-021-01269-2
  • 贝蒂TF, Stotts AL, Suchting R, et AL。洗手会导致尼古丁从吸烟的人的手指中删除不完全：一个随机对照实验[在线印刷前在线发布，2021年10月11日]。Am J Perinatol。2021; 10.1055/s-0041-1736287。doi：10.1055/s-0041-1736287
  • Profit J, Adair KC, Cui X, et al. Randomized controlled trial of the “WISER” intervention to reduce healthcare worker burnout. J Perinatol. 2021;41(9):2225-2234. doi:10.1038/s41372-021-01100-y
  • Adams-Chapman I，Watterberg KL，Nolen TL等。在肌醇随机对照试验中招募的早产儿的神经发育结果。J Perinatol。2021; 41（8）：2072-2087。doi：10.1038/s41372-021-01018-5
  • 贝蒂TF, Stotts AL, Suchting R, et AL。Thirdhand smoke associations with the gut microbiomes of infants admitted to a neonatal intensive care unit: An observational study. Environ Res. 2021;197:111180. doi:10.1016/j.envres.2021.111180
  • Kumbhat N, Eggleston B, Davis AS, et al. Umbilical Cord Milking vs Delayed Cord Clamping and Associations with In-Hospital Outcomes among Extremely Premature Infants. J Pediatr. 2021;232:87-94.e4. doi:10.1016/j.jpeds.2020.12.072
  • Northrup TF，Suchting R, Green C,Khan A, Klawans MR, Stotts AL. Duration of breastmilk feeding of NICU graduates who live with individuals who smoke. Pediatr Res. 2021;89(7):1788-1797. doi:10.1038/s41390-020-01150-6
  • Gupta VS,可汗AM，Ebanks AH等。Cornelia de Lange综合征和先天性diaphragmatragmatic疝。J Pediatr Surg。2021; 56（4）：697-699。doi：10.1016/j.jpedsurg.2020.06.003
  • Laptook AR, Shankaran S, Barnes P, et al. Limitations of Conventional Magnetic Resonance Imaging as a Predictor of Death or Disability Following Neonatal Hypoxic-Ischemic Encephalopathy in the Late Hypothermia Trial. J Pediatr. 2021;230:106-111.e6. doi:10.1016/j.jpeds.2020.11.015
  • Kumbhat N, Eggleston B, Davis AS, et al. Placental transfusion and short-term outcomes among extremely preterm infants. Arch Dis Child Fetal Neonatal Ed. 2021;106(1):62-68. doi:10.1136/archdischild-2019-318710
  • 贝蒂TF, Stotts AL, Suchting R, et AL。Thirdhand Smoke Contamination and Infant Nicotine Exposure in a Neonatal Intensive Care Unit: An Observational Study. Nicotine Tob Res. 2021;23(2):373-382. doi:10.1093/ntr/ntaa167
  • Kirpalani H, Bell EF, Hintz SR, et al. Higher or Lower Hemoglobin Transfusion Thresholds for Preterm Infants. N Engl J Med. 2020;383(27):2639-2651. doi:10.1056/NEJMoa2020248
  • Northrup TF，Suchting R, Klawans MR, et al. Proactive delivery of nicotine replacement therapy to families of hospitalized infants in a NICU: A randomized controlled pilot trial. J Neonatal Nurs. 2020;26(4):201-206. doi:10.1016/j.jnn.2020.01.002
  • Arnold C，Tyson JE，Pedroza C等。循环光疗剂量调查研究针对极低的产生婴儿：一项随机临床试验[已发表的校正出现在JAMA PEDIATR中。2020年7月1日； 174（7）：732]。贾马丘脑。2020; 174（7）：649-656。doi：10.1001/jamapediatrics.2020.0559
  • Stotts AL，Northrup TF，Green C等。在高危婴儿中减少烟草烟雾暴露：一项随机，对照试验。J Pediatr。2020; 218：35-41.e1。doi：10.1016/j.jpeds.2019.10.070
  • 贝蒂TF, Stotts AL, Suchting R, et AL。医疗staff contributions to thirdhand smoke contamination in a neonatal intensive care unit.烟草诱发疾病。2019;17:37. Published 2019 Apr 24. doi:10.18332/tid/106116
  • Findley TO, Shah A, Bell C,Khan A。The value of serial newborn screening for congenital hypothyroidism using thyroxine (T4) in the neonatal intensive care unit.J Perinatol。2019;39(8):1065-1071. doi:10.1038/s41372-019-0400-3
  • Sedlock EW, Ottosen M, Nether K, et al. Creating a comprehensive, unit-based approach to detecting and preventing harm in the neonatal intensive care unit. Journal of Patient Safety and Risk Management. 2018;23(4):167-175. doi:10.1177/2516043518787620
  • Szafranski P, Kośmider E, Liu Q, et al. LINE- and Alu-containing genomic instability hotspot at 16q24.1 associated with recurrent and nonrecurrent CNV deletions causative for ACDMPV.哼声。2018; 39（12）：1916-1925。doi：10.1002/humu.23608
  • De Jesus-Rojas W, Mosquera RA, Samuels C, et al. The Effect of Comprehensive Medical Care on the Long-Term Outcomes of Children Discharged from the NICU with Tracheostomy.开放式呼吸医学j。2018;12:39-49. Published 2018 Jul 31. doi:10.2174/1874306401812010039
  • Laptook AR, Shankaran S, Tyson JE, et al. Effect of Therapeutic Hypothermia Initiated After 6 Hours of Age on Death or Disability Among Newborns With Hypoxic-Ischemic Encephalopathy: A Randomized Clinical Trial [published correction appears in JAMA. 2018 Mar 13;319(10 ):1051.JAMA。2017; 318（16）：1550-1560。doi：10.1001/jama.2017.14972
  • Shankaran S，Laptook AR，Pappas A等。缺氧 - 缺血性脑病的深度和冷却持续时间对18个月的死亡或残疾的影响：一项随机临床试验。JAMA。2017; 318（1）：57-67。doi：10.1001/jama.2017.7218
  • Holzmann‐Pazgal G,可汗AM，Northrup T，Domonoske C，Eichenwald EE抗菌剂
    Utilization in the Neonatal Intensive Care Unit (NICU): A Pressing Need for Stewardship,
    Open Forum Infectious Diseases, Volume 3, Issue suppl_1, Fall 2016, 1928,
    https://doi.org/10.1093/ofid/ofw172.1476
  • Mendez-Figueroa H，Truong VT，Pedroza C，可汗AM, Chauhan SP. Small-for-gestational-age infants among uncomplicated pregnancies at term: a secondary analysis of 9 Maternal-Fetal Medicine Units Network studies.Am J Obstet Gynecol。2016;215(5):628.e1-628.e7. doi:10.1016/j.ajog.2016.06.043
  • Northrup TF，可汗AM, Jacob P 3rd, et al. Thirdhand smoke contamination in hospital settings: assessing exposure risk for vulnerable paediatric patients.Tob Control。2016;25(6):619-623. doi:10.1136/tobaccocontrol-2015-052506
  • Holzmann-Pazgal G,可汗AM，Northrup TF，Domonoske C，Eichenwald EC。在新生儿重症监护病房中减少万古霉素的利用。是J感染控制。2015;43(11):1255-1257. doi:10.1016/j.ajic.2015.06.028
  • Northrup TF，Matt GE，Hovell MF，可汗AM，Stotts al。在医学上脆弱的儿童之家中的第三次吸烟：评估室内吸烟水平和吸烟禁令的影响。尼古丁TOB Res。2016; 18（5）：1290-1298。doi：10.1093/ntr/ntv174
  • Shankaran S，Laptook AR，Pappas A等。深度和冷却持续时间对缺血性缺血性脑病的新生儿中NICU死亡的影响：一项随机临床试验。JAMA。2014; 312（24）：2629-2639。doi：10.1001/jama.2014.16058
  • Stotts AL, Northrup TF, Schmitz JM, et al. Baby’s Breath II protocol development and design: a secondhand smoke exposure prevention program targeting infants discharged from a neonatal intensive care unit.Contemp Clin Trials。2013;35(1):97-105. doi:10.1016/j.cct.2013.02.012
  • Holzmann-Pazgal G，Kubanda A，Davis K，可汗AM, Brumley K, Denson SE. Utilizing a line maintenance team to reduce central-line-associated bloodstream infections in a neonatal intensive care unit.J Perinatol。2012;32(4):281-286. doi:10.1038/jp.2011.91
  • Pepiak DL, Alcorn JL, Atkins CL, Xue H, Colasurdo GN,可汗AM。Effects of infant formula on cell homeostasis and cytokine levels in an in vivo and in vitro murine aspiration model.Pediatr Pulmonol。2011年,46岁(9):927-933. doi:10.1002/ppul.21444
  • Chen MG, Atkins CL, Bruce SR,可汗AM，刘Y，Alcorn JL。婴儿配方奶粉在肺上皮细胞中改变表面活性剂蛋白A（SP-A）和SP-B表达。Pediatr Pulmonol。2011年,46岁(9):903-912. doi:10.1002/ppul.21455
  • Shah SK,可汗AM, Cox CS Jr. Pulmonary hypertensive crisis requiring ECMO associated with re-warming from whole body hypothermia for hypoxic ischemic encephalopathy: clinical observations from a case series.Eur J Pediatr Surg。2010;20(3):205-206. doi:10.1055/s-0029-1241872
  • Castro SM，Guerrero-Plata A，Suarez-Real G等。抗氧化剂治疗可以缓解呼吸道合胞病毒诱导的疾病和肺部炎症。Am J Respir Crit Care Med。2006;174(12):1361-1369. doi:10.1164/rccm.200603-319OC
  • Colasurdo GN, Fullmer JJ, Elidemir O, Atkins C,可汗AM，Stark JM。在囊性纤维化的鼠模型中，呼吸道合胞病毒感染。J Med Virol。2006;78(5):651-658. doi:10.1002/jmv.20589
  • Fullmer JJ,可汗AM, Elidemir O, Chiappetta C, Stark JM, Colasurdo GN. Role of cysteinyl leukotrienes in airway inflammation and responsiveness following RSV infection in BALB/c mice.Pediatr Allergy Immunol。2005;16(7):593-601. doi:10.1111/j.1399-3038.2005.00248.x
  • 可汗AM, Lally KP. The role of extracorporeal membrane oxygenation in the management of infants with congenital diaphragmatic hernia.Semin Perinatol。2005; 29（2）：118-122。doi：10.1053/j.semperi.2005.04.005
  • Stark JM,可汗AM, Chiappetta CL, Xue H, Alcorn JL, Colasurdo GN. Immune and functional role of nitric oxide in a mouse model of respiratory syncytial virus infection.J感染Dis。2005;191(3):387-395. doi:10.1086/427241
  • Weisoly DL,可汗AM，Elidemir O，Smith KC。先天性结核病需要体外膜氧合。Pediatr Pulmonol。2004;37(5):470-473. doi:10.1002/ppul.10423
  • Miller J，Colasurdo GN，可汗AM, et al. Immunocytochemical detection of milk proteins in tracheal aspirates of ventilated infants: a pilot study.Pediatr Pulmonol。2002;34(5):369-374. doi:10.1002/ppul.10189
  • 可汗AM, Elidemir O, Epstein CE, et al. Meconium aspiration produces airway hyperresponsiveness and eosinophilic inflammation in a murine model.AM J生理肺细胞分子生理。2002;283(4):L785-L790. doi:10.1152/ajplung.00335.2001
  • Cochran JR,可汗AM，Elidemir O等。脂多糖暴露对发育中的小鼠气道功能和过敏反应的影响。Pediatr Pulmonol。2002;34(4):267-277. doi:10.1002/ppul.10161
  • 可汗AM，Lally KP，Elidemir O，Colasurdo GN。胎粪增强了人类气道上皮细胞中一氧化氮的释放。新生儿杂志。2002;81(2):99-104. doi:10.1159/000047192
  • 可汗AM，Lally KP，Larsen GL，Colasurdo GN。人类气道上皮细胞暴露于胎粪后，血栓烷A（2）的释放增强。Pediatr Pulmonol。2002; 33（2）：111-116。doi：10.1002/ppul.10058
  • Gill BS, Neville HL,可汗AM，Cox CS JR，Lally KP。体外膜氧合的延迟机构与死亡率增加和住院时间长期有关。J Pediatr Surg。2002; 37（1）：7-10。doi：10.1053/jpsu.2002.29417
  • Gitomer JJ,可汗AM, Ferris ME. Treatment of severe theophylline toxicity with hemodialysis in a preterm neonate.Pediatr Nephrol。2001;16(10):784-786. doi:10.1007/s004670100650
  • 可汗AM, Shabarek FM, Kutchback JW, Lally KP. Effects of dexamethasone on meconium aspiration syndrome in newborn piglets.Pediatr Res。1999;46(2):179-183. doi:10.1203/00006450-199908000-00009
  • 可汗AM，Shabarek FM，Zwischenberger JB等。每日头部超声检查婴儿对体外膜氧合的婴儿的效用。J Pediatr Surg。1998; 33（8）：1229-1232。doi：10.1016/s0022-3468（98）90156-7

Certifications

American Board of Pediatrics, General Pediatrics, 1995
美国儿科委员会，新生儿 - 仇恨医学，2003年