CeTIR Overview

CeTIR is a part of the Department of Surgery, McGovern Medical School at the University of Texas Health Science Center at Houston (UTHealth) and works in partnership with Memorial Hermann - Texas Medical Center (MH-TMC). CeTIR has designed and implemented as well as participated in a wide variety of studies in trauma, burn and traumatic brain injury. CeTIR’s research activities have directly impacted patient care and have resulted in a reduction in overall mortality from 7.1% to 5.7% despite a 13% increase in admissions and a reduction in mortality related to damage control laparotomies from 18.9% to 7.1%.

Activities include:

• Partnership with MH-TMC, one of the busiest Level 1 trauma center in the U.S.
• Access to 7000 trauma admissions annually (~3000 are considered highest activation)
• Air ambulance services transport approximately 1500 highest activation patients
• Blood products are available on helicopters
• Conducted 6 multicenter trials as the Clinical Coordinating Center and/or Data Coordinating Center which included:
• Prospective Observational Multicenter Major Trauma Transfusion (PROMMTT) study
• Pragmatic Randomized Optimal Platelet and Plasma Ratios (PROPPR) trial
• Prehospital Resuscitation on Helicopter Study (PROHS)
• Provide research implementation and administration services to faculty, fellows, residents and medical students at UTHealth and the McGovern Medical School
• Provide educational opportunities for medical students, residents, fellows and junior faculty
• Support 5 research fellows (3 T32 and 2 postdoctoral research fellows)
• Support 5 - 10 summer medical students every summer
• Provide 24/7 personnel coverage for research-related activities, including research sample collection and analysis
• Ongoing collection of data from all highest activation adult trauma patients admitted to MH-TMC and coordination with MH-TMC trauma registry
• 参与研究导致超过80526 published manuscripts
  • Studies include:
    • Randomized interventional
    • Prospective observational
    • Retrospective
    • Federally and industry-funded
    • Investigator-initiated and sponsor-initiated
• Multicenter collaborations with 26 universities and institutions including international
• Faculty and staff have submitted 19 different patent filing applications resulting in 10 patent applications and 1 copyright registration.
• Obtained nearly $90 million in federal, state, private, and industry grant and contract funding since September 2008 and have applied for $22.8 million in the current fiscal year.