Dr. Do Monte received his bachelor’s degree in veterinary medicine from Universidade do Estado de Santa Catarina in Brazil (2002), and his master’s and PhD degrees (general pharmacology and neuropharmacology) from Universidade Federal de Santa Catarina in Brazil, under the mentorship of Dr. Antônio P. Carobrez. His master dissertation was directed to understand the mechanisms involved in the expression of both innate and learned fear memories (2006). His doctorate thesis was focused on elucidating the noradrenergic mechanisms mediating the extinction and reconsolidation of aversive memories (2010). As a postdoctoral fellow in Dr. Gregory Quirk’s laboratory in the Department of Psychiatry at the University of Puerto Rico, Dr. Do Monte investigated the neural circuits regulating the retrieval of fear memories and the crucial role of the passage of time in the reorganization of these memories. During his postdoctoral training, he was awarded the prestigious “NIH pathway to independence award (K99/R00)” from the National Institute of Mental Health. Dr. Do Monte became an Assistant Professor in the McGovern Medical School at UTH in 2016, where he has recently been awarded a Rising STARs Award from the UT System.

beplay苹果手机能用吗研究信息

DO Monte Lab的重点是理解情感记忆的神经回路和机制。我们特别有兴趣阐明恐惧和奖励相关的记忆如何相互作用以产生最适应性的行为反应。使用大鼠的多学科方法,我们结合了光遗传学,体内电生理记录,药理学,免疫组织化学和成像技术,研究涉及恐惧和奖励刺激的机制,重点是对捕食者提示引起的先天性防御反应。

哺乳动物的大脑具有将厌恶和有益的刺激与环境提示联系起来的非凡能力。有害和有益刺激之间的正确歧视使生物体可以选择最合适的反应,从而保护其免受危险。在人类中,相关记忆的不当检索是滥用药物的框架,而不当的恐惧/厌恶记忆的检索可能会导致焦虑症的发展。了解介导恐惧和奖励相关记忆的整合的神经回路可能会发现患有焦虑和药物有关的成瘾性疾病的患者更有效的疗法。

出版物

出版信息

  • Fernandez-León*,Ja;Engelke*,DS;Aquino-Miranda*,G;古德森,一个;做蒙特,FH。前额叶皮层的神经相关性和决定因素。审查。(可在生物xivs2021.05.27.445881)。view PDF
  • De Oliveira-Alvares,L和做蒙特,FH。Understanding the dynamic and destiny of memories.神经科学和生物行为评论。125,592-607,2021。view PDF
  • Engelke, DS; Zhang, XO; O’Malley, J; Fernandez-Leon, JA; Li, S; Kirouac, GJ; Beierlein, M;做蒙特,FH。下丘脑 - 丘脑纹状体电路,可控制大鼠的避免进路冲突。自然通讯。12(1):2517,2021。view PDF
  • 陈,Y;男人;pei,z;Wu,Z;做蒙特,fh;Keefel,S;Yellin,E;陈,M;Yin,J;Lee,G;小型托里比奥,a;hu,y;bai,y;韭葱; Quirk, GJ; Chen, G. A NeuroD1 AAV-based gene therapy for functional brain repair after ischemic injury through in vivo astrocyte-to-neuron conversion.分子疗法;28(1),237-234,2020。view PDF
  • Do Monte,FH和Kirouac,GJ。丘脑D2多巴胺能传播的增强:寻求药物衰减的潜在策略。Eneuro,21; 4(6),2017年。
  • 做蒙特,fh*;小型托里比奥*,a;Quiñones-Laracuente,K;Medina-Colón,EM;Quirk,GJ。意外奖励遗漏期间对蔗糖寻求的丘脑调节。神经元,94(2):388–400.E4,2017
  • Martínez-Rivera,FJ;Rodríguez-Romaguera,J;Lolet-Torres,我;蒙特,跳频;Quirk GJ,Barreto-Estrada,JL。通过深脑刺激腹侧纹状体刺激药物灭绝的双向调节。生物精神病学,80(9):682-690,2016。
  • 蒙特,跳频;Quirk,GJ;李,b;马萨诸塞州彭佐。随着时间的流逝,取回恐惧记忆。分子精神病学,21(8):1027-1036,2016。view PDF
  • 罗萨斯 - 维达尔,le;Rodriguez-Romaguera,J;蒙特,跳频;Andero,R。针对灭绝记忆的重新整合:一种治疗焦虑症的新型潜在策略。分子精神病学,20(11):1264-5,2015。view PDF
  • 做蒙特,fh*;Manzano-Nieves*,G;Quiñones-Laracuente,K;Ramos-Medina,L;Quirk,GJ。重新审视侵入性皮质在恐惧灭绝光遗传学中的作用。神经科学杂志,,,,35(8):3607-3615,2015。view PDF(根据Web of Science,在出版12个月后12个月的学术领域中最多的1%的论文)。
  • 蒙特,跳频;Quiñones-Laracuente,K;Quirk GJ。电路的暂时转变,介导了恐惧记忆的检索。自然,519(7544):460-463,2015。view PDF(根据网络科学的说法,在出版12个月后,学术领域的最高1%的论文最高的论文)
    • Commentary featured in the journal “Nature Reviews Neuroscience”: Yates, D. (2015). Neural circuits: a nucleus of fear.自然Reviews Neuroscience16,121)。view PDF
  • Rodriguez-Romaguera,J;蒙特,跳频;Tanimura,Y;Quirk,GJ;哈伯,sn。大脑刺激的增强恐惧灭绝:内侧轨道额受累的证据。神经心理药理学,40(7):1726-1733,2015。view PDF
  • Bravo-Rivera,C;Diehl,MM;罗马 - 奥蒂斯(C);Rodriguez-Romaguera,J;罗萨斯 - 维达尔,le;Bravo-Rivera,H;Quiñones-Laracuente,K和Do Monte,FH。前额叶皮层调节行为中的远程GABA能神经元。神经生理学杂志,,,,114:1357-1359,2014view PDF
  • 罗萨斯 - 维达尔,le;蒙特,跳频;Sotres-bayon,f;Quirk,GJ。海马前额外的bdnf和记忆恐惧灭绝,神经心理药理学,39(9):2161-2169,2014。view PDF
  • 蒙特,跳频;Rodriguez-Romaguera,J;罗萨斯 - 维达尔,le;Quirk,GJ。Deep brain stimulation of the ventral striatum increases BDNF in the fear extinction circuit.行为神经科学领域。7:102,2013。
  • 蒙特,跳频;Souza,RR;Bitencourt,RM;JA KROON;高桥,RN。将大麻二醇输注到输卵管皮层中有助于通过CB1受体灭绝。行为大脑研究beplay苹果手机能用吗,250C:23-27,2013。
  • 做蒙特,fh*;souza,rr*;Wong,TT;Carobrez,美联社。prazosin的全身性或原内皮层输注会损害恐惧记忆的重新整合。行为大脑研究beplay苹果手机能用吗,,,,244:137-141,2013。view PDF
  • Rodriguez-Romaguera,J*;做蒙特,fh*;Quirk GJ。深脑刺激腹纹状体会增强条件恐惧的消失。美国国家科学院论文集 - 美国,,,,109(22):8764-8769,2012。view PDF
  • Padilla-Coreano*,n;做蒙特,fh*;Quirk,GJ。中线丘脑核在恐惧记忆的检索中的时间依赖性作用。神经药理,62(1):457-463,2012。view PDF
  • 蒙特,跳频;Kincheski,G;Pavesi,E;Sordi,R;Assreuy,J;Carobrez,美联社。β-肾上腺素能受体在大鼠背景恐惧灭绝期间腹膜前额叶皮层中的作用。学习和记忆的神经生物学,,,,94(3):318-328, 2010.view PDF
  • 加利福尼亚州斯特恩;蒙特,跳频;Gazarini,L;Carobrez,美联社;Bertoglio,LJ。在升高的迷宫重新测试期间调整焦虑反应水平是必需的。神经科学,,,,170:214 - 222,2010。view PDF
  • 蒙特,跳频;Allensworth, M; Carobrez, AP. Impairment of contextual conditioned fear extinction after microinjection of alpha-1-adrenergic blocker prazosin into the medial prefrontal cortex.行为大脑研究beplay苹果手机能用吗,,,,211:85 - 95,2010。view PDF
  • 蒙特,跳频;NS坎特拉斯;Fernandes,D;Assreuy,J;Carobrez,美联社。β-肾上腺素能与生俱来的新观点和恐惧对捕食者气味的反应。神经科学杂志,28(49):13296-13302,2008。view PDF
  • NS坎特拉斯;JA KROON;蒙特,跳频;Pavesi,E;Carobrez,美联社。通过嗅觉系统传感危险:下丘脑背骨上核核的作用。神经科学和生物行为评论,,,,32:1228-1235,2008。view PDF
  • 桑托斯小詹;Blanco,MM;蒙特,跳频;马萨诸塞州的俄罗斯;Lanziotti,VM;Leal,LK;通用汽车。水醇提取物的镇静和抗惊厥作用Equisetum arvenseFitoterapia,76:508-513,2005。view PDF
  • 桑托斯小詹;蒙特,跳频;Blanco,MM;Lanziotti,VM;Maia,FD;Leal,LK。长期给药后,老年大鼠认知增强Equisetum arvense l。具有体外证明的抗氧化特性。药理学生物化学和行为,81:593-600,2005。view PDF
  • 桑托斯小詹;Tabosa,a;蒙特,跳频;Blanco,MM;弗里雷,AO;梅洛,勒。电针可防止毛果皮 - 癫痫大鼠的认知缺陷。神经科学信件,384:234-238,2005。view PDF
  • 蒙特,跳频;桑托斯小詹;马萨诸塞州的俄罗斯;Lanziotti,VM;Leal,LK;通用汽车。Antinociceptive and anti-inflammatory properties of the hydroalcoholic extract of stems fromEquisetum arvenseL.在老鼠中。药理研究beplay苹果手机能用吗,,,,49:239 - 243,2004。view PDF
  • 桑托斯小詹;蒙特,跳频;Russi,妈,奥古斯汀,P, Lanziotti,VM. Proconvulsant effects of high doses of venlafaxine in pentylenetetrazole-convulsive rats.巴西医学与生物学研究杂志beplay苹果手机能用吗,,,,35:469 - 472,2002。view PDF

*表示平等的作者身份