Last update: February 21, 2022
CICADA: Clinical informatics and computational approaches for drug-repositioning
Project Period:08/01/2021-07/31/2026
Agency:University of Pennsylvania/NIHPI:Cui Tao, Yong Chen (UPenn) (MPI)
Goal:该项目的总体目标是开发新颖的临床信息学和计算方法，以重新定位AD/ADRD。具体而言，研究人员将开发统计方法和本beplay苹果手机能用吗体技术，以从多维数据（例如，与药学连接的遗传数据和生物库数据，历史试验和EHR数据）中提取药物替代信号。该提出的框架是新颖的，因为它将高级统计推理程序与语义技术集成在一起，用于数据驱动和可重复的AD/ADRD药物重新定位。
对新创新癌症预防研究人员的合作培训beplay苹果手机能用吗
Project Period:2021-2026
Agency:CPRITPI:Fernandez, Mullen, Swindell, Tao (MPI)
Goal:培训博士前和博士后研究研究员。beplay苹果手机能用吗
AI-based conversational agent for facilitating education and communication about HPV vaccination in children and adolescents
Project Period:3/1/2022-2/28/2026
Agency:CPRITPI:Cui Tao
Goal:Development of an interactive conversational agent to enhance HPV vaccine awareness to decision makers (patients or parents of patients). The work involves a dialogue system that enriches a speech-enabled software agent to have prolonged, consistent, and lightweight counseling with a health consumer where the agent drives the conversation about the HPV vaccine. The results of the research team’s efforts will be a software agent that protects the privacy of the patient and is independent of third-party proprietary software vendors.
Using big data and deep learning on predicting HIV transmission risk in MSM population
Project Period:09/01/2020 - 08/31/2022
Agency:NIHPI:Cui Tao, Kayo Fujimoto, John Schneider (MPI)
Goal:The goal of this project aims at predicting HIV transmission risks using advanced informatics approaches.
Dynamic learning for post-vaccine event prediction using temporal information in VAERS
Project Period:02/01/2017 - 01/31/2022
Agency:NIHPI:Cui Tao (PI), Yong Chen (MPI)
Goal:该项目的目的是开发新颖的信息学和统计方法，以动态预测疫苗接种后的不良反应。
对患者双重抗血小板疗法的人工智能辅助个性化使用大规模电子健康记录进行了冠状动脉支架实施
Project Period:12/01/2019-11/30/2023
Agency:啊哈PI:Cui Tao
Goal:In this project, we will develop and validate novel deep learning methods for evaluating the risk of bleeding and ischemic events (e.g. life-threating bleeding, thrombosis and myocardial infarction) after coronary artery stent implantation so as to suggest personalized DAPT duration through learning pattern from large-scale electronic health records.
Facilitate observational studies of Alzheimer's Disease and Alzheimer's Disease-related dementias using ontology and Natural Language Processing
Project Period:05/01/2021-04/30/2024
Agency:NIHPI:Hua Xu, Cui Tao, and Hongfang Liu (Mayo Clinic) (MPI)
Goal:该项目将开发新的本体论和自然语言处理（NLP）方法和工具，以提取和标准化临床信息，以了解观察性阿尔茨海默氏病/阿尔茨海默氏病与疾病相关的痴呆症（AD/ADRD）研究。beplay苹果手机能用吗
癫痫的风险标记ide的信息框架ntification and risk assessment
Project Period:05/15/2020-04/30/2025
Agency:NIHPI:Licong Cui
Goal:The main goal of this project is to develop a SUDEP Risk Marker Extraction system for automated extraction of known and putative SUDEP risk markers from the multimodal patient data collected by the Center for SUDEP Research from Epilepsy Monitoring Units in multiple medical centers.
审核和增强本体完整性的方法
Project Period:08/31/2021-08/31/2026
Agency:NIHPI:Licong Cui
Goal:该项目的主要目标是开发自动化和可扩展的方法，以识别生物医学本体论中潜在的不完整问题，并建议解决这些方法来解决这些问题。
An interface ontology for Alzheimer’s disease research
Project Period:09/15/2020 - 05/31/2022
Agency:NIHPI:Licong Cui
Goal:该项目的主要目的是开发一个新颖的阿尔茨海默氏病（AD）研究和基于Web的数据勘探工具，用于管理，查询和探索广告数据资源。beplay苹果手机能用吗
生物医学术语质量保证，用于增强电子健康记录的临床查询
Project Period:08/01/2020 - 07/31/2022
Agency:NIHPI:Licong Cui
Goal:The main goal of this project is to develop a general automatic change-suggestion framework to systematically address quality issues in biomedical terminologies and to quantitatively assess the terminology quality impact on clinical queries over EHRs for patient cohort identification.
CAREER: Advancing the Role of Ontologies for Data Science in Biomedicine
Project Period:09/01/2021-08/31/2026
Agency:NSFPI:Licong Cui
Goal:该项目的目的是提高本体在生物医学中的数据科学的作用，并解决语义互操作性和本体质量的关键障碍。
Informatics tools to improve the interpretability and interoperability of informed consent instruments
Project Period:09/16/2020-09/15/2021
Agency:NIHPI:Cui Tao (PI), Amy Franklin (Co-I), Muhammad Amith (Co-I)
Goal:This project addresses the permissions statements in consent forms, starting with permissions for collection, sharing, and reuse of specimens and associated data. Specifically, we aim to build a prototype of an application that leverages semantic metadata about permissions in consent forms, and to identify participant friendly terminology for permissions that can be linked to Informed Consent Ontology terms with the same meaning, facilitating computability and strong linkages with other terminology systems.
Metadata applications on informed content to facilitate biorepository data regulation and sharing
Project Period:09/28/2016-07/31/2020
Agency:NIHPI:Cui Tao
Goal:This proposed study will focus on (1) developing a standard conforming metadata ontology to formally represent the informed consent domain; and (2) an automatic tool to semantically annotate informed consent documents to facilitate biorepository data regulation, sharing, and decision support.
EHR数据的患者病史表示，提取和推断
Project Period:09/01/2014 - 08/31/2020
Agency:NIHPI:Cui Tao
Goal:该项目将为EHR开发一个基于本体和语义的时间关系建模和推理工具。
An ontology-driven faceted query engine for the Kentucky Cancer RegistryProject Period:06/06/2018 - 07/31/2021
Agency:NIHPI:Licong Cui & GQ Zhang (MPI)
Goal:The main goal of this project is to develop OncoSphere, a novel ontology-driven faceted query system to enhance web-based exploration of Kentucky Cancer Registry data.