UTHealth as Reviewing IRB
UTHealth IRB may be the reviewing IRB for a multi-site study. CPHS has been the IRB of record for several Clinical Trial Xpress trials. CPHS has also been the reviewing IRB when a research study involves other investigators in other institutions in collaborating roles e.g. samples are sent to another institution for analysis as part of a research study.
For multi-site studies, before agreeing to be the IRB of record, ensure that UTHealth IRB is wiling and able to be the Reviewing IRB.
Effective January 25, 2018, NIH-funded multi-site studies, where each site will conduct the same protocol involving non-exempt human subjects research, whether supported through grants, cooperative agreements, contracts, or the NIH Intramural Research Program must use a single Institutional Review Board (sIRB). This requirement applies to all competing NIH grant applications (new, renewal, revision or re-submission) with submission date on or after Jan 25, 2018. For more information on choosing an sIRB and budgeting requirements, please visit here. (go to sIRB page)
A request for UTHealth IRB to be the reviewing IRB must be made via iRIS. The request may be made at the time of initial submission or later as a change request. The submission packet for requesting UTHealth IRB to be the reviewing IRB should include, for each relying site:
- Permission letter from the relying institution
- 完全的Addition of PI formfor each relying institution
- 带有本地PI信息的同意书（如果适用）
- Local context information (if requested by UTHealth IRB)
IRB工作人员将检查Uthealth是否与依赖机构达成协议。如果没有，IRB工作人员将与依赖机构合作签订IRB依赖协议。Uthealth IRB将发出一封信，表明加入依赖机构已获得批准。通过此批准，Uthealth IRB将对依赖机构的研究进行IRB监督。beplay苹果手机能用吗提交和审查的要求也可能因Uthealth IRB与依赖机构之间的协议条款而有所不同。
For more detailed guidance on managing IRB communication the UTHealth PI is the lead PI and the UTHealth IRB is the reviewing IRB, pleaseclick here.