A study designed to determine how magnetic resonance imaging (MRI) can be used to help clinicians treat patients with brain hemorrhages is underway at The University of Texas Health Science Center at Houston (Uthealth休斯顿).

The trial, led by穆罕默德哈克，博士，assistant professor of neurology with McGovern Medical School at UTHealth Houston and the UTHealth Institute for Stroke and Cerebrovascular Disease, is investigating a special MRI protocol to help understand which patients might be at risk for hematoma expansion and determining when patients might be safely placed back on anti-thrombotic medications such as aspirin. Hematoma expansion is a pool of clotted blood that can occur after a blood vessel breaks.

目前的护理标准是计算断层扫描（CT）扫描，用于检测任何出血的非侵入性X射线。CT和MRI扫描都能够定位和检测血肿膨胀，但HAQUE认为对现有的MRI方案的微小修饰可以区分血肿内的凝结（或凝血）与血肿内的非刻录物（或非凝血）血液区分。

“我们正在研究MRI是否可以提供更完整的信息，这可以改变出血性卒中患者的临床管理，”Haque表示。“对于患者的全面评估，CT扫描的目前的实践是不充分的。我们寻求帮助提供商提供将有助于他们提前干预的信息，并且甚至可能会消除不必要的外科手术。我们的最终目标是采取此数据，并进行广泛研究此成像方法。“

脑内出血 - 一种脑内出血的脑渗出，脑组织内的任何位置 - 占所有笔触的约10％至15％，与高死亡率有关。它是最常见的是高血压的结果，这可能导致薄壁动脉将血液带到大脑内部的区域以破裂，将血液释放到脑组织中。随着血液泄漏并对大脑压力施加压力，它被剥夺了氧气和血液供应。脑细胞死亡，由此产生的炎症反应在血肿周围的区域损害更多细胞。

There is a 30%-40% mortality rate for intracerebral hemorrhage, Haque said, with 73% of patients experiencing some degree of hematoma growth, and with about one-third of them exhibiting hematoma expansion – a 33% growth of hematoma volume within 24 hours of intracerebral hemorrhage.

“With this MRI sequence, we hope to see within the hematoma what percentage of the blood is already clotted and what percentage is in the liquid form,” Haque said. “We will determine if patients with mostly clotted blood are less likely to see their blood expand.”

该研究于10月以来一直在纪念Hermann-Texas Medical Center举行的研究，该学会由唯一的Star Stroke财团资助，该联盟是德克萨斯州领先的医学研究机构之间的合作，以改善受卒中和脑血管病影响的德克塞人的健康。beplay苹果手机能用吗

Among others, the consortium is helmed by study co-investigators James Grotta, MD, director of stroke research with the Clinical Institute for Research and Innovation at Memorial Hermann-TMC and neurologist with the Memorial Hermann Medical Group, andSean Savitz, MD,professor and the Frank M. Yatsu, MD, Chair in Neurology with McGovern Medical School.Jaroslaw Aronowski, MD, PhD,professor and the Roy M. and Phyllis Gough Huffington Chair in Neurology with McGovern Medical School, is also a study co-investigator.

Grotta founded the stroke program at UTHealth Houston in 1979. Today, Savitz directs the UTHealth Stroke Institute, and Aronowski is a member of the institute. Savitz and Aronowski are also faculty members with The University of Texas MD Anderson Cancer Center Graduate School of Biomedical Sciences.

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