Course Descriptions
- 肿瘤免疫学在临床环境中的应用
Course Detail
GS06 1132（2个学分）
落下Naing, Aung. Two semester hours. Fall, annually. Grading System: Letter Grade. Prerequisite: Previous immunology course such as免疫学or consent of the instructor prior to enrollment.
本课程以基本免疫学为基础，为肿瘤免疫学提供基础，因为它在临床环境中应用。参与本课程的研究生，博士后研究员和医疗居民/研究员将了解免疫监测，肿瘤标记，人类肿瘤免疫反应，新颖的癌症免疫治疗药，调节过程以及用于癌症免疫治疗药的临床试验设计。
- Basic and Translational Cancer Biology
Course Detail
GS04 1235（5个学分）
春天Hu, Jian; Ying, Haoqing. Five semester hours. Spring, annually. Grading System: Letter Grade. Prerequisite: None. Audit Permitted.
The Cancer Biology Core course will synthesize knowledge of critical aspects
in 人类癌症生物学用于了解疾病发展，多维分子特征，诊断和治疗学。课程委员会赞扬2020-2021学年课程
- 单细胞数据分析的计算方法
Course Detail
GS01 1041(1学分)
春天和落下钦，肯；尼古拉斯的纳文；王，温耶。一个学期。每年春季和秋季。分级系统：通过/失败。先决条件：无。允许审核。
本课程旨在提供单细胞研究实验设计和分析所需的中心概念和背景知识。该格式将期刊俱乐部和研讨会系列格式结合在一起，并有组织地阅读了单细胞奥米奇技术中的里程碑式论文，高维数据分析（包括转换，可视化和聚类），统计推断，统计建模和系统发育学等等可能的主题。会有参与者演讲和讨论会议。在课程结束时，学生将能够对单细胞研究进行批判性思考，并了解他们在癌症研究和其他学科中的应用。beplay苹果手机能用吗
Schedule can be found这里。
- 免疫学的新兴概念
Course Detail
GS06 1103 (3 credits)
落下Akimzhanov，Askar。三个学期。每年秋天。评分系统：字母等级。Prerequisite:Fundamental Immunology（GS06 1013）或讲师的同意。允许审核。
本课程的主要目的是向学生传授免疫学领域中使用的最新发现和技术。在选定领域的主要专家的指导下，学生将对顶级期刊进行批判性评估和介绍出版物。主题领域包括抗原加工，淋巴细胞，补体，肿瘤微环境，T和B淋巴细胞，疫苗和佐剂，免疫疗法，CAR T细胞和单频抗体的基本，转化和临床研究。该课程通常运行10周，每周两次会议，每次会议2小时
- Fundamental Immunology
Course Detail
GS06 1013（3个学分）
春天Ekmekcioglu，Suhendan。三个学期。春季，每年。评分系统：字母等级。Prerequisites: Undergraduate-level Biology and Biochemistry courses plus a basic knowledge of cellular and molecular biology.
本讲座系列涵盖的主题包括解剖学和免疫系统的发展；抗体的结构，功能和遗传学；T细胞抗原受体；淋巴样细胞的功能和合作相互作用；由主要的组织相容性复合物（MHC）编码的分子的结构和功能；淋巴动物及其受体；细胞相互作用分子；和特定的免疫耐受性。将从基础科学的角度涵盖的医学相关受试者包括免疫病理学，免疫缺陷，过敏和其他超敏反应，自身免疫，器官移植，肿瘤免疫学和艾滋病。
- Introduction to Bioinformatics
Course Detail
GS01 1143（3个学分）
春天陈，肯
和 Navin, Nicholas. Three-credit hour. Spring, annually. Grading System: Letter Grade.本课程旨在成为生物信息学中概念和方法的介绍，重点是分析来自高吞吐量实验管道（例如下一代测序）合并的数据。学生将接触到参与数据处理和生物学解释各个方面的算法和软件工具。尽管强烈建议一些先前的编程经验，但这不是必需的。
- 细胞信号的分子基础
Course Detail
GS13 1024（4个学分）
春天Du, Guangwei. Four semester hours. Spring, annually. Grading System: Letter Grade. Prerequisites: Background in biochemistry and cell biology; Consent of instructor.
This course provides a detailed exploration of the molecular basis of cell signaling with emphasis on recent developments, structure-function, and quantitation. The course will include both the regulation of second messenger systems (GPCRs, G proteins, cAMP, IP3 and lipid), ion channels, growth factor-regulated tyrosine kinases, small G proteins (ras, GEFs, Gaps), kinase/phosphatase pathways, steroid hormones/transcription, and the modeling of these systems.
- 遗传学和表观遗传学原理
Course Detail
GS04 1253 (3 credits)
春天克拉，拉尔夫；玛格丽达桑托斯；卡普尔，阿什什。三个月的小时。每年春季。评分系统：字母等级。先决条件：GS21 1017/18：生物医学研究的基础。beplay苹果手机能用吗允许审核。
The Principles of Genetics and Epigenetics class is designed for students who have a major interest in the aspects of experimental and human genetics and epigenetics as they relate to human disease, including Mendelian disorders, complex diseases and cancer. Students are required to have completed the core course. This class will provide in-depth instruction on four areas: 1) Experimental genetics, 2) Human genetics, 3) Epigenetics, 4) Functional bioinformatics. The class will be held two times a week for one and a half hours. Students are expected to actively participate in the course by initiating discussions, asking questions, and providing constructive comments, as well as completing bi-weekly homework assignments based on the material covered in the lectures. Students will be evaluated by attendance, participation, and overall performance on the assigned homework. This course is designed to prepare the student to generate novel hypothesis-driven projects in the areas of genetics and epigenetics.
- Principles of Stem Cell Biology
Course Detail
GS04 1072(2 credits)
春天戴维斯（Davis），布莱恩（Brian）和吉（Yoshimoto），Momoko。两个学期。春季，每年。先决条件：教练的同意
Stem cells, be they embryonic or somatic, play crucial roles in the development and functional maintenance of individual organ systems and complete organisms. As has already been well demonstrated for the blood-forming system through bone marrow transplantation, stem cells can be utilized clinically for treatment of genetic or acquired diseases. The next couple of decades will undoubtedly provide many more successful clinical applications of stem cells in regenerative medicine. Stem cells may also play critical roles themselves in the initiation and maintenance of certain diseases, such as cancer. This course will provide a present-day understanding of the precise definition, molecular characterization, and biological function of stem cells. Our focus will primarily be on fundamental issues regarding stem cells, as well as on their wide range of potential future applications. Completion of this course will adequately prepare students to both identify and understand fundamental issues in current stem cell research, as well as to contribute themselves to advancing this field through research.
- 治疗原则
Course Detail
GS04 1103（3个学分）
春天张，分流。三个学期。春季，每年。评分系统：字母等级。先决条件：本科生生物化学和生物学。
本课程将在革命制度党建立基础nciples of therapeutics, lectured by >35 experts including 1/3 basic research faculty, 1/3 clinical faculty, and 1/3 pharma/biotech industry veterans. It starts with discussions on disease processes, through therapy development, then to clinical translation. The course is grouped into a series of general topics. The first topic includes disease mechanisms in microbial, viral, fungal, neurodegenerative, and malignant settings in order to better understand the nature of the problems. The second topic focuses on the development of lead molecules and drug design, including x-ray crystallography, molecular modeling, hit identification, lead optimization, and pharmacokinetic/pharmacodynamic studies. The third topic puts emphasis on drug screening methodologies, including high-throughput/content technologies and molecular imaging as well as in vitro and in vivo preclinical model systems. The fourth topic covers different therapeutic modalities and improved drug delivery systems. It also describes the latest development of immunotherapy, cell therapy, gene therapy, and stem cell transplantation. The fifth topic focuses on the identification of novel molecular targeting strategies and efforts toward individualization of therapy with state-of-the-art –omics technologies and biomarker development. The final topic group focuses on translating therapeutic strategies to the clinic, including the phases of preclinical studies, clinical trial design and execution, and regulatory considerations.将有三个考试；每个占最终成绩的33.33％。考试结构是基于论文的。
课程委员会赞扬学年课程2020-2021
- 癌症转移的生物学
Course Detail
GS04 1093 (3 credits)
落下Frigo, Daniel; Li, Wenliang.三个学期。每年秋天。评分系统：字母等级。先决条件：讲师的同意。
一个教学介绍水平课程完全致力于研究基于癌症转移的细胞生物学过程。本课程将涵盖基本，转化和临床知识，具体重视转移性级联：种子和土壤假设，器官特异性转移，细胞周期和转移，多种转移性癌症的多种疗法，并将解决基本的过程research to the clinic (‘bench-to-bedside') for major metastatic human cancers.
这是癌症发现曲目中癌症生物学学生的先决条件。