UthealthHouston researchers analyze cancer discrepancies among young Black men in the South

Research shows that incidences of Kaposi’s sarcoma among people living with HIV have fallen significantly over the past two decades, but a new evaluation of data led by researchers atUthealthHouston突出了一个特定人群的显着差异 - 美国南部的年轻黑人。

该研究的结果今天在JNCI癌症谱of the National Cancer Institute.

Kaposi的肉瘤是一种罕见的癌症，经常在患有艾滋病毒/艾滋病或其他免疫缺陷的患者中被诊断出。它是从细胞淋巴或血管的细胞中发展出来的，通常以皮肤或口腔内的肿瘤出现，但也可以出现在整个体内的淋巴结中。

Evaluating 18 years of data (2001-2018) from the Centers for Disease Control and Prevention National Program of Cancer Registries (NPCR) and National Cancer Institute Surveillance, Epidemiology, and End Results Program Database (SEER),休斯顿公共卫生学院researchers found that while Kaposi’s sarcoma rates among men age 20-34 were decreasing nationally among white men at a rate of 3.5% per year, and holding steady among Hispanic men, incidence rates among Black men actually increased by 1.5% per year. In the South, the increase was even more dramatic, jumping by 3.3% per year. By 2018, this group would account for 62% of the national percentage of Black men in that age group diagnosed with the cancer; an increase of nearly 20%. Further analysis demonstrated that Black men born since 1994 in the South had more than double the risk of Kaposi’s sarcoma as compared to those born before 1979.

Combined with the work of other researchers, the evidence gleaned from the analysis suggests that the observed increase in Kaposi’s sarcoma among Black men in the South is primarily related to parallel increases in HIV infection among young Black men living there who have sex with men. While NPCR and SEER registry data does not include HIV/AIDS status, prior research suggests that the vast majority of Kaposi’s sarcoma cases in the age group are HIV-positive. Higher levels of poverty and HIV-related stigma in the South also likely contribute to the higher incidence of the cancer. In addition to those two factors, lack of access to medical care and sexual/social network dynamics may also contribute to the ongoing and disproportionate rise in Kaposi’s sarcoma incidence among the studied group.

“The future public health interventions should focus on addressing multilevel social determinants of health to reduce these existing racial and regional disparities,” said Ryan Suk, PhD, lead author and assistant professor of health economics at UTHealth Houston School of Public Health.

nPCR-SEER registries covered approximately 98% of the U.S. population between 2001 and 2018. The data set included 3,838 men with complete race and ethnicity information, between the ages of 20 and 34, and diagnosed with Kaposi’s sarcoma. Of those, 46% were Black, and 24.1% were white. The remaining men included members of Hispanic and other racial and ethnic groups.

研究小组beplay苹果手机能用吗还包括唐娜l .白色,PhD, MPH, assistant professor of medicine at Baylor College of Medicine, Houston; Sheena Knights, MD, assistant professor of internal medicine at UT Southwestern Medical Center, Dallas; Ank Nijhawan, MD, MPH, associate professor of internal medicine at UT Southwestern; Ashish A. Deshmukh, PhD, MPH, associate professor of public health sciences at the Medical University of South Carolina, Charleston; and Elizabeth Y. Chiao, MD, MPH, professor of epidemiology at The University of Texas MD Anderson Cancer Center, Houston.